Guests of the Meson De San Sebastian Hotel Puebla enjoy a variety of attractions in the city, including museums and churches. El Parian is a local arts and crafts market. One of the most popular points of interest, the magnificent Puebla Cathedral, took 300 years to complete. Other historic sites include the Municipal Palace, Museo Amparo, and the Palafoxiana Library. Covered parking is available at the Meson De San Sebastian Hotel Puebla for guests arriving by car. Hermanos Serdan Airport is the closest major airport to the hotel.

The Meson De San Sebastian Hotel Puebla offers 17 private guestrooms with amenities like televisions, phones, and coffee service.

The hotel is housed in a Baroque building that was built sometime in the 1600s. The interior retains both old and new architectural features. The hotel restaurant offers room service for dining convenience, while the bar is the perfect spot to enjoy a cocktail. Services include a currency exchange, cloakroom, conference space, and a hotel safe. The front desk of the Meson De San Sebastian Hotel Puebla is open 24 hours. Laundry service is available.